| Core positioning | OpenAI official lightweight Python/JS SDK focused on multi-agent handoffs, tool calling, tracing, and Realtime API with deep OpenAI model integration | Google official full-stack Agent development framework covering Python/Java/Go, emphasizing Gemini model and Google Cloud ecosystem integration |
| Best for | Small-medium projects using OpenAI models, needing Realtime voice agents, and multi-agent handoff workflows | Medium-large enterprise Agent applications using Gemini models, needing multi-language support and Google Cloud integration |
| Multi-agent collaboration | Built-in Handoffs primitive, agents transfer control via message handoffs, model automatically decides handoff timing | Built-in SubAgent and SequentialAgent components, supports LLM-driven and workflow two orchestration modes |
| Deployment and ecosystem | Local Python/JS process or container deployment, native integration with OpenAI suite (Realtime, TTS, Whisper) | Supports local, Vertex AI Agent Engine, Cloud Run multiple deployment modes, deep integration with Google Cloud services |